Acute Glomerulonephritis

11/05/2010 Etiology and Pathophysiology of Acute Glomerulonephritis (AGN) Acute glomerulonephritis (AGN) is officious irritation in the glomeruli. Each kidney is composed of about 1 one million million microscopic filtering screens known as glomeruli that selectively remove uraemic waste products. The inflammatory process usually begins with an infection or injury (e.g., burn, trauma), then the protective immune system fights head the infection, scar create from raw stuff forms, and the process is complete. at that place atomic number 18 some(prenominal) diseases that suit of clothes an combat-ready inflammation within the glomeruli. Some of these diseases be systemic (i.e., early(a) parts of the body atomic number 18 convoluted at the very(prenominal) time) and some occur solely in the glomeruli. When there is active inflammation within the kidney, scar tissue may transpose normal, functional kidney tissue and cause permanent nephritic impairment. The rig our and extent of glomerular damagefocal (confined) or spread out (widespread)determines how the disease is manifested. Glomerular damage fag end come out as subacute renal failure, progressive inveterate renal failure (CRF); or simply a urinary unregularity such as hematuria (blood in the urine) or proteinuria (excess protein in the urine).

Primary diseases that solely affect the kidneys and cause AGN, imply the following: * Immunoglobulin A nephropathy (IgA nephropathy, Bergers disease) * Membranoproliferative nephritis (type of kidney inflammation) Postinfectious GN (GN that results after an infection In diffuse glomerulonephritis (GN), all of the glomeruli are agg ressively feelered, leading to acute renal ! failure (ARF) Disorders that set upon several organs and cause diffuse GN and they are referred to as a secondary causes. Which include the following: * Cryoglobulinemia * Goodpasteurs syndrome (membranous antiglomerular home cellar membrane disease) * Lupus nephritis * Vasculitis (e.g., Wegeners granulomatosis, periarteritis nodosa) * Postinfectious GN (GN that results after an...If you want to reduce a full essay, order it on our website: OrderEssay.net

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